Medical-research-skills response-letter

Source: https://github.com/aipoch/medical-research-skills

When to Use

• You received peer-review comments and need a point-by-point response letter for journal resubmission.
• You must clearly map every manuscript change to a specific location (page/paragraph/line) for reviewers or editors.
• You need a consistent, professional response structure across multiple reviewers and revision rounds.
• You are coordinating an internal review and want a standardized change log and execution checklist.
• You need a Word (.docx) deliverable rather than a table-based response format.

Key Features

• Consolidates, merges, and numbers reviewer comments across reviewers.
• Separates major vs. minor comments to prioritize revision work.
• Produces a fixed, repeatable response layout per comment:
  • Reviewer’s Comment
  • Response
  • Changes in Text
• Requires explicit change-location marking (page/paragraph/line) and version labeling.
• Supports quoting revised manuscript text (e.g., blockquotes) to make changes auditable.
• Generates a Word (.docx) response letter plus a modification/execution checklist.
• Adds an Overview for the Editor section summarizing major revisions at the beginning.
• Enforces a professional, polite tone throughout.

Dependencies

• Microsoft Word

  .docx

  output (Word-compatible document generation)
• Reference format guide:

  references/guide.md

Example Usage

Input:
- Manuscript (tracked version or clean version + change notes)
- Reviewer comments (all reviewers, all rounds)
- Current manuscript pagination/line numbering scheme (if available)

Steps:
1) Organize comments
   - Merge all reviewer comments into a single list.
   - Number them sequentially (e.g., R1-1, R1-2…; R2-1…).
   - Tag each as Major or Minor.

2) Draft "Overview for the Editor"
   - Write one concise paragraph summarizing the major revisions and their rationale.

3) Write point-by-point responses
   For each numbered comment, output:
   - Reviewer’s Comment: (verbatim or lightly cleaned for clarity)
   - Response: (polite, direct, addresses the request)
   - Changes in Text: (what changed + where)

4) Mark locations and quote revised text
   - Provide page/paragraph/line for each change.
   - Specify additions/deletions.
   - Quote the revised paragraph when the main text is modified.

5) Generate deliverables
   - Export the full response letter as a Word document (.docx).
   - Produce a modification/execution checklist to verify all changes are applied.

Output (Word .docx structure):
- Title / Manuscript info (optional)
- Overview for the Editor
- Responses to Reviewer 1
  - R1-1
  - R1-2
  ...
- Responses to Reviewer 2
  ...
- Modification / Execution Checklist

Implementation Details

• Comment normalization and numbering
  • Merge comments from all sources; assign stable IDs (e.g.,

    R{reviewer}-{index}

    ) to preserve traceability across revision rounds.
• Major vs. minor classification
  • Major: requests affecting study design, analyses, interpretation, or core claims.
  • Minor: wording, formatting, clarifications, citations, typos.
• Per-comment fixed layout
  • Each response must include three labeled blocks: Reviewer’s Comment, Response, Changes in Text.
• Location marking
  • Use page/paragraph/line when available; otherwise use section/subsection headings plus paragraph index.
  • Always indicate whether text was added, deleted, or rewritten.
• Revised-text excerpting
  • When the manuscript body changes, include the updated paragraph as an indented blockquote under Changes in Text for auditability.
• Output constraints
  • Final deliverable is a Word document (

    .docx

    ).
  • Do not use table format for the response letter.
• Formatting and checklists
  • Follow

    references/guide.md

    for required output formats, checklist items, and key writing points.