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ClawBio omics-target-evidence-mapper

Aggregate public target-level evidence across omics and translational sources for research triage.

install
source · Clone the upstream repo
git clone https://github.com/ClawBio/ClawBio
Claude Code · Install into ~/.claude/skills/
T=$(mktemp -d) && git clone --depth=1 https://github.com/ClawBio/ClawBio "$T" && mkdir -p ~/.claude/skills && cp -r "$T/skills/omics-target-evidence-mapper" ~/.claude/skills/clawbio-clawbio-omics-target-evidence-mapper && rm -rf "$T"
manifest: skills/omics-target-evidence-mapper/SKILL.md
source content

Why This Exists

Researchers often need a quick first-pass view of whether a gene or protein target has evidence across multiple public sources. In practice, this usually means checking several websites manually and informally combining results. This skill makes that process reproducible by retrieving and organising public evidence into one structured output.

This skill is for research triage only. It does not infer causality, rank therapeutic value, or make clinical recommendations.

Core Capabilities

  1. Accept a gene or protein target and an optional disease term.
  2. Retrieve canonical target information from UniProt.
  3. Retrieve disease-target association evidence from Open Targets.
  4. Retrieve recent literature hits from PubMed.
  5. Optionally retrieve trial records relevant to the target and disease.
  6. Produce a machine-readable JSON file and a human-readable Markdown report.

Input Formats

ArgumentRequiredExampleNotes
--gene
Yes, unless 
--demo
is used
IL6R
Gene or target symbol
--disease
No
coronary artery disease
Optional disease context
--output
Yes
demo_out
Output directory
--max-papers
No
5
Number of PubMed hits to include
--max-trials
No
5
Number of trial records to include
--demo
No
--demo
Runs the built-in demo query

Workflow

  1. Validate CLI inputs.
  2. Resolve the query from either user input or demo mode.
  3. Query public data sources.
  4. Normalise results into a structured evidence object.
  5. Write JSON and Markdown outputs.
  6. Write file checksums for reproducibility.

CLI Reference

Demo mode

python skills/omics-target-evidence-mapper/omics_target_evidence_mapper.py --demo --output demo_out