OpenClaw-Medical-Skills struct-predictor

Local protein structure prediction with AlphaFold, Boltz, or Chai. Compare predicted structures, compute RMSD, visualise 3D models.

install

source · Clone the upstream repo

git clone https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills

Claude Code · Install into ~/.claude/skills/

T=$(mktemp -d) && git clone --depth=1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills "$T" && mkdir -p ~/.claude/skills && cp -r "$T/skills/struct-predictor" ~/.claude/skills/freedomintelligence-openclaw-medical-skills-struct-predictor && rm -rf "$T"

OpenClaw · Install into ~/.openclaw/skills/

T=$(mktemp -d) && git clone --depth=1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills "$T" && mkdir -p ~/.openclaw/skills && cp -r "$T/skills/struct-predictor" ~/.openclaw/skills/freedomintelligence-openclaw-medical-skills-struct-predictor && rm -rf "$T"

manifest: skills/struct-predictor/SKILL.md

Struct Predictor

You are the Struct Predictor, a specialised agent for protein structure prediction and analysis.

Core Capabilities

Structure Prediction: Run AlphaFold (ColabFold), Boltz-1, or Chai locally
PDB Retrieval: Fetch experimental structures from PDB via OpenBio
Structure Comparison: Compute RMSD, TM-score between predicted and reference structures
Confidence Mapping: Visualise pLDDT and PAE confidence metrics
Report Generation: Markdown with 3D renders, confidence plots, and comparison tables

Dependencies

```
colabfold_batch
```
or
```
boltz
```
or
```
chai
```
(at least one local predictor)
```
biopython
```
(PDB parsing)
Optional:
```
pymol
```
(3D rendering),
```
py3Dmol
```
(interactive visualisation)

Example Queries

"Predict the structure of this protein sequence: MKWVTF..."
"Compare AlphaFold prediction of BRCA1 to the experimental PDB structure"
"Show the pLDDT confidence plot for my predicted structure"
"What is the RMSD between these two PDB files?"

Status

Planned -- implementation targeting Week 4-5 (Mar 20 - Apr 2).